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Sanofi

Syndol Tablets

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Syndol contains four different medicines called caffeine, codeine phosphate, doxylamine succinate and paracetamol. Paracetamol acts as an analgesic (painkiller) and an antipyretic (lowers body temperature), codeine phosphate is an analgesic, doxylamine succinate is an antihistamine and caffeine is a mild stimulant.

1. What is it used for?

Syndol is used for the short term treatment of acute moderate pain which is not relieved by paracetamol, ibuprofen and aspirin alone such as headache, including muscle contraction or tension headache, migraine, neuralgia, period pain, toothache and other dental pain, muscular and rheumatic aches and pains and for pain relief following surgery or dental procedures.

Codeine can be used in children over 12 years of age for the short-term relief of moderate pain that is not relieved by other painkillers such as paracetamol or ibuprofen alone but not if they are under 18 years of age and have had their tonsils or adenoids removed due to Obstructive Sleep Apnoea Syndrome.

2. What you need to know before you take Syndol

Do not take Syndol if
• you are allergic to codeine, paracetamol, doxylamine succinate, caffeine or any of the ingredients of this medicine. Signs of an allergic reaction include a rash and breathing problems. There can also be swelling of the legs, arms, face, throat or tongue
• you are having an asthma attack or have severe breathing problems
• you have recently had a head injury
• you have been told by your doctor that you have increased pressure in your head. Signs of this include headaches, being sick (vomiting) and blurred eyesight
• you have recently had an operation on your liver, gall bladder or bile duct (biliary tract)
• you are at risk of blocked intestine (paralytic ileus)
• you are taking other medicines containing codeine or any other paracetamol-containing products
• you are taking a medicine of the class known as Monoamine Oxidase Inhibitors (MAOIs, e.g. selegiline, moclobemide), which are used as antidepressants, or if you had taken any medicine of this group in the past 14 days.
• you are an alcoholic
• the person going to take the tablets is under 12 years of age
• you are under 18 years of age and have had your tonsils or adenoids removed due to Obstructive Sleep Apnoea Syndrome
• you know that you metabolise very rapidly codeine into morphine
• you are breast-feeding or planning to breastfeed

Do not take Syndol if any of the above apply to you.

3. How do you take it?

Adults over 18 years of age:
• Take one or two tablets every four to six hours as needed for relief
• Adults should wait at least 4 hours before taking another dose
• Do not take more than eight tablets in a 24 hour period
• Do not exceed the stated dose

If you are elderly or of a weakened state you should seek advice from your doctor before taking Syndol as dosage adjustment may be required.

Children aged 16 to 18 years
1 to 2 tablets every 6 hours when necessary up to a maximum of 8 tablets in 24 hours

Children aged 12 to 15 years
1 tablet every 6 hours when necessary up to a maximum of 4 tablets in 24 hours

Children under 12 years
Syndol should not be taken by children below the age of 12, due to the risk of severe breathing problems.

4. Possible side effects?

Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:
• constipation
• headache
• drowsiness
• dizziness
• restlessness
• difficulties passing urine
• dry mouth
• blurred vision
• diarrhoea
• thick phlegm

Stop taking Syndol and see a doctor or go to a hospital straight away if:
• You have a rash, fever, swelling, bruising or tiredness
• You have difficulty in breathing or you feel dizzy
• You get swelling of the hands, feet, ankles, face, lips or throat which may cause difficulty in swallowing or breathing
• You could also notice an itchy, lumpy rash (hives) or nettle rash (urticaria). This may mean you are having an allergic reaction
• You get serious skin reactions. Very rare cases have been reported.

    Syndol Tablets.

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    Learn more about Syndol Tablets

    • 1. What is Syndol?

    • 2. How does it work?

    • 3. How is it used?

    • 4. How do you store it?

    The ideal short-term solution for relief from moderate to acute pain, especially in instances where paracetamol, ibuprofen, or aspirin alone has not worked.

    Syndol Tablets are for short-term treatment and should only be taken for pain that is not relieved by paracetamol, ibuprofen, or aspirin alone, and should not be taken for more than 3 days at a time.

    Always take Syndol exactly as your doctor or pharmacist has told you, or first check with them if you are not sure.

    Adults and those aged 65+:
    Take one or two tablets every four to six hours as needed for relief.
    Wait at least 4 hours before taking another dose.
    Do not take more than eight tablets in a 24 hour period.

    Children aged 16 to 18 years:
    Take 1 to 2 tablets every 6 hours when necessary up to a maximum of 8 tablets in 24 hours.

    Children aged 12 to 15 years:
    Take 1 tablet every 6 hours when necessary up to a maximum of 4 tablets in 24 hours.

    Children under 12 years:
    Syndol should not be taken by children below the age of 12, due to the risk of severe breathing problems.
    Do not take Syndol for more than 3 days.
    If you need to use this medicine for more than three days you must speak to your doctor or pharmacist.

    - Keep out of the sight and reach of children
    - Do not use after the expiry date shown on the details of packaging
    - The expiry date refers to the last date of that month
    - Store below 25°C in the original packaging to protect from moisture
    - Do not throw away medicines via household waste
    - Ask your pharmacist how to throw away medicines you no longer use

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    About Pain Relief

    1. About Pain Relief

    Pain is an experience everyone will have from time to time in their life. Pain has different levels and can range from a mild knock that hurts for a few moments to excruciating pain you feel when you seriously injure yourself. No matter what the severity you should always identify the cause of the pain and get the relevant treatment to heal this.

    Depending on the cause of pain, you will both experience different ranges of pain and for different lengths of time. Pain can also have a knock on effect on your day to day life, for example, sleep can be affected by pain, leaving the individual weak and tired, which in turn can lead to other conditions such as a migraine.

    2. What causes Pain?

    Pain is caused by messages running through an individuals' nervous system in their body whenever there is damage, inflammation or irritation in the body, these pain sensors send electric signals directly to the brain which is translated as pain.

    Individuals experience different levels of pain depending on the situation as the brain sends the necessary amount of ""pain strength"" based on the severity of the problem, and where its located.

    Once the source of pain has been treated, these signals stop getting sent to the brain and you no longer feel the pain sensation on that area. However there is occasion where individuals continue you to feel pain after treated, this is known as chronic pain. Chronic pain usually effects those with underlying medical conditions such as arthritis. It can also occur because the individual has damage to the nervous system.

    3. How can Pain be managed?

    Whether your pain is long-term or has just started, the NHS recommends trying the following ten self-help steps. Get some gentle exercise to ease pain as it blocks pain signals to the brain, concentrate on your breathing, read books and leaflets on pain, get counselling to deal with emotions related to pain, distract yourself with another activity, share your story about pain, try to improve your sleep routine, take a self management course, keep in touch with friends and family and relax to beat pain, practicing relaxation techniques can help to reduce persistent pain.

    More information about pain management - https://www.nhs.uk/conditions/end-of-life-care/controlling-pain-and-other-symptoms/

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